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Contribute to nagilum/Code39Barcode development by creating an account on GitHub. barcode generator for ssrs CONNECTIVE The anatomic features previously mentioned enable TISSUE EN one to conceptualize the possible avenues by which SPACE disease may affect the peripheral nerves Pathologic PM SA processes may be directed at any one of the several groups of nerve cells whose axons constitute the nerves, ie, the cells of the anterior or lateral horns EP of the spinal cord, the dorsal root ganglia, or symP RS pathetic and parasympathetic ganglia Each of these cell types exhibits speci c vulnerabilities to disease processes, and if destroyed as, for example, the SUBARACHNOID motor nerve cells in poliomyelitis there results a SPACE secondary degeneration of the axons and myelin sheaths of the peripheral bers of these cells Neuropathic symptoms may also be induced by alteraEN tions of function and structure of the ventral and PM dorsal columns of the spinal cord, which contain SA RS the bers of exit and entry of anterior horn and EP dorsal root ganglion cells, respectively The myelin of these centrally located bers is constituted difCONNECTIVE A ferently from that of the peripheral nerves, being TISSUE DM enveloped by oligodendrocytes rather than Schwann SPACE cells, and the bers are supported by astrocytes Figure 46-1 Diagram showing the relationships of the peripheral nerve sheaths to the merather than broblasts ningeal coverings of the spinal cord The epineurium (EP) is in direct continuity with the dura Because of the intimate relation of the nerve mater (DM) The endoneurium (EN) remains unchanged from the peripheral nerve and spinal roots to the CSF and to specialized arachnoidal root to the junction with the spinal cord At the subarachnoid angle (SA), the greater portion cells (the arachnoidal villi), a pathologic process in of the perineurium (P) passes outward between the dura mater and the arachnoid (A), but a the CSF or leptomeninges may damage the exposed few layers appear to continue over the nerve root as part of the root sheath (RS) At the spinal roots Disease of the connective tissues may subarachnoid angle, the arachnoid is re ected over the roots and becomes continuous with the affect the peripheral nerves that lie within their outer layers of the root sheath At the junction with the spinal cord, the outer layers of the sheaths Diffuse or localized arterial diseases may root sheath become continuous with the pia mater (PM) (From Haller FR, Low FM: Am J injure nerves by occluding their nutrient arteries In Anat 131:1, 1971, by permission) a large category of immune-mediated neuropathies, is blocked, with subsequent neuronal destruction; poisoning with damage is the result of a cellular or humoral attack on various arsenic, which combines with the axoplasm of the largest sensory components of myelin A subset of these is characterized by the and motor nerves via sulfhydryl bonds; and vincristine toxicity, binding of circulating antibodies to the specialized regions at the which damages the microtubular transport system Analogous annodes of Ranvier, causing a block of electrical conduction Also, a atomic pathways are probably implicated in other diseases by complement-dependent, humoral immune reaction against the radmechanisms that remain to be discovered icular or peripheral axon is known Toxic or immunologic agents Among the genetically determined neuropathies, the altered that selectively damage the Schwann cells or their membranes, gene products are now known in some cases to lead to defective cause demyelination of peripheral nerves leaving axons relatively myelination, which greatly slows conduction along nerves In other intact, or a toxin may speci cally affect axons by poisoning their genetic diseases it is speculated that structural components of the cell bodies, the axolemma, or the lengthy and complex axonal axon are disrupted, leading to axonal degeneration and impaired transport apparatus Finally, one might correctly suppose that axons electrical conduction of the motor or sensory nerves, sympathetic bers of varying diameter and length, or the end organs to which they are attached would each have its own particular liability to disease Pathologic Reactions of Peripheral Some of this is theoretical and somewhat speculative At Nerve present we can cite only a few examples of diseases or toxins that cause disease through these mechanisms exclusively: eg, diphthePathologically, several distinct processes are recognized in the peria, in which the bacterial toxin acts directly on the membranes of ripheral nerve, although they are not disease-speci c and may be the Schwann cells near the dorsal root ganglia and adjacent parts present in varying combinations in any given case The classic ones of motor and sensory nerves (the most vascular parts of the peare segmental demyelination, wallerian degeneration, and axonal ripheral nerve); polyarteritis nodosa, which causes widespread ocdegeneration (diagrammatically illustrated in Fig 46-2) clusion of vasa nervorum, resulting in multifocal nerve infarction; The myelin sheath is the most susceptible element of the nerve tabes dorsalis, in which there is a treponemal meningoradiculitis of ber, for it may break down as part of a primary process involving the posterior roots (mainly of the lumbosacral segments) that lie the Schwann cells or the myelin sheath itself, or it may be damaged next to the arachnoidal villi where CSF is resorbed; doxorubicin secondarily, as a consequence of disease affecting its axon Focal intoxication, wherein protein synthesis of dorsal root ganglion cells degeneration of the myelin sheath with sparing of the axon is called. c# create code 39 barcode Packages matching Tags:"Code39" - NuGet Gallery
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