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audits to more complex processes like Total Quality Management to detect mistakes and misdeeds. Trustees examine the strategic past via dashboards, benchmarks, and scorecards, as well as official progress reports. But in both cases, the past comes to the board compressed, aggregated, and prefabricated. Rather than working with management to create the story line, the board listens while management relates the story. For generative governance, boards need to use the past to make sense of options for the future. The key tools for this work are retrospective questioning and dominant narratives. Most board members can dutifully recite the institution s strategic priorities for the next three to five years, but few can explain the institution s successes or setbacks over the past three to five years.Yet constructing explanations about past performance often yields new strategies, insights, or innovations. Useful explanations start with questions that uncover unrecognized strengths, unnoticed flaws, and incipient patterns: Why was the college able to increase dramatically both the quantity and quality of applicants without additional offers of financial aid Why did the aquarium fail to fulfill strategic priorities of advocacy and education How did the school achieve national recognition in the sciences when that was not an explicit element of the formal long-range plan Why does the organization s staff, board, and clientele remain homogeneous despite an explicit and pervasive commitment to diversity What is the most important problem we tackled in the last year What was the most important lesson we learned in the process

After 4 h, a 27-fold increase in endotoxin concentration was observed in the cI -infected culture, in contrast to the six- and sevenfold increases in the supernatant of cultures infected with M13S105 and M13R, respectively In a related study, Hagens et al (2004) developed a genetically engineered, non-replicating, non-lytic phage based on phage Pf3 to combat an experimental P aeruginosa infection An export protein gene of the P aeruginosa lamentous phage Pf3 was replaced with BglII This rendered the Pf3 variant (Pf3R) non-replicative and prevented the release of the therapeutic agent from the target cell The Pf3R phage ef ciently killed a wild-type host in vitro, while endotoxin release was kept to a minimum Treatment of P aeruginosa infections of mice with Pf3R or with a replicating lytic phage resulted in comparable survival rates upon challenge.

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interrupt the power to your home. Or the lightning stroke may cause the lights in your home to bli nk. This momentary varia-

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However, the survival rate following phage therapy with Pf3R increased (compared with the lytic phage) when the mice were challenged with a higher concentration of P aeruginosa This higher survival rate correlated with a reduced in ammatory response elicited by Pf3R treatment relative to that with the lytic phage Therefore, this study suggests that the increased survival rate.

Button faces are handled in the Options tab. Click the Options tab and select Icon Only from the Layout pull-down menu. Click the Choose Icon button and the Select Icon dialog box opens. From this dialog box you need to access yet another dialog box by clicking the Browse button. The Open dialog box opens to a view where you can navigate your hard drive and select a file to import as your button face. Any file format compatible with the Create PDF from File tool is acceptable. Select a filename in the Open dialog box and click Select. Acrobat returns you to the Select Icon dialog box where you can see a preview of the imported file, as shown in Figure 22.37.

but to give the reader the tools needed to take knowledge of these patterns and get work done. Also included in Part Two is a chapter on Alternatives to Entity Beans, which gives an EJB developer s perspective on using Java Data Objects (JDO) to persist an object model, and a chapter on more fine-grained design tips and strategies that were too small to qualify as full patterns. I would recommend that you read through the patterns in Part One before proceeding to Part Two. If you are more of a hands-on type, you can start reading through the first few chapters of Part Two and refer to the patterns in Part One when they are mentioned.

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